With the advanced analytical technologies in monitoring the nuclear activities with
mass spectrometry, Korea Atomic Energy Research Institute introduced the thermal
ionization mass spectrometry coupled with scanning electron microscopy (SEMTIMS)
and satisfied the requirements of qualification for the NetWork of Analytical
Laboratories (NWAL) using the recent isotopic analysis of uranium particles in the
6th Nuclear Signatures Interlaboratory Measurement Evaluation Programme
(NUSIMEP-6) sample.
A lipidome profile method was established for the phosphatidylinositol 3,4,5-
trisphosphates on mammalian cells with LC/MS to investigate the phosphate and
tensine homolog(PTEN) enzymatic activity in cells. In addition, a fast drug
pharmacokinetic evaluation method was developed using an ultra-fast generic LCMS/
MS method with the optimized ballistic gradient and flow rate. In order to
develop Dioscin, a biologically active steroidal saponin, as a future cancer treating
medicine, a reliable, selective and sensitive LC-MS/MS method was established to
evaluate pharmacokinetic behavior in rat plasma.
I would like to appreciate your contribution on the next special issue for the former
Korean Society for Mass Spectrometry president Dr. Hun Young So. For the special
issue, article submissions will be closed by November 30 and will be published
before the end of December 2013.
Sincerely Yours,
Hyun Sik Kim,
Editor-in-Chief, Mass Spectrometry Letters
Invited Article
41
Analysis of Phosphatidylinositol 3,4,5-Trisphosphates of PTEN Expression on Mammalian Cells
Phosphoinositides, Lipidomics, PTEN, Mass Spectrometry, Enzymatics
Nusrat Jahan, Taeseong Park, Young Hwan Kim, Dongsun Lee, Hackyoung Kim, Young Jun Kim
Letter
47
Ultra-fast Generic LC-MS/MS Method for High-Throughput Quantification in Drug Discovery
LC-MS/MS, high-throughput quantification, drug discovery, ballistic gradient system
So-Hee Kim, Hye Hyun Yoo, Eun-Ju Cha, Eun Sook Jeong, Ho Jun Kim, Dong Hyun Kim, Jaeick Lee
51
Isotopic Analysis of NUSIMEP-6 Uranium Particles using SEM-TIMS
Journal Information
Vol 4 No3 September 2013 
